Platelet Rich Fibrin (PRF)
Platelet Rich Fibrin (PRF)
PRF, or Platelet Rich Fibrin, harnesses the healing properties of blood platelets, which contain numerous growth factors crucial for the healing process. These growth factors interact with stem cells in the targeted area, prompting tissue regeneration. Unlike PRP (Platelet Rich Plasma), PRF undergoes a distinct processing method to incorporate more than just platelets. It includes additional cells such as white blood cells (WBC), cytokines, and Mesenchymal Stem Cells, without the use of additives or anticoagulants. Consequently, the natural clotting process occurs, with fibrin acting as a mesh to secure platelets in the injected area, facilitating an extended release of growth factors over 7-10 days for enhanced healing and regeneration.
Difference between PRF and PRP:
- Both PRF and PRP originate from the patient’s own blood and utilize its growth factors to stimulate tissue regeneration.
- PRP is processed at a higher speed and for a longer duration to separate all cells from the platelets and contains anticoagulants to maintain the blood concentrate’s viscosity for longer injection times.
- PRF, on the other hand, is processed at a lower speed and for less time, retaining concentrated platelets along with WBCs and Mesenchymal stem cells. PRF lacks additives or anticoagulants, leading to rapid clot formation upon injection. The fibrin mesh formed within the clot enables the gradual release of growth factors, mimicking the natural healing process of the body.
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